Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts

Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts

Besides being traditionally used to relieve hepatobiliary disorders, Cynara cardunculus L. has evidenced anticancer potential on triple-negative breast cancer (TNBC). This study highlights the antiproliferative effects of lipophilic extracts from C. cardunculus L. var. altilis (DC) leaves and floret...

Full description

Bibliographic Details
Main Authors: Patrícia A. B. Ramos, Ângela R. Guerra, Olinda Guerreiro, Sónia A. O. Santos, Helena Oliveira, Carmen S. R. Freire, Armando J. D. Silvestre, Maria F. Duarte
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
Cynara cardunculus L. var. altilis (DC)
lipophilic extracts
cynaropicrin
taraxasteryl acetate
triple-negative breast cancer MDA-MB-231 cell line
p21Waf1/Cip1 upregulation
phospho(Tyr15)-CDK1 protein accumulation
phospho(Ser473)-Akt downregulation
Online Access:http://www.mdpi.com/1422-0067/18/1/63

Internet

http://www.mdpi.com/1422-0067/18/1/63

Similar Items