Impairment of GABA transporter GAT-1 terminates cortical recurrent network activity via enhanced phasic inhibition
In the central nervous system, GABA transporters (GATs) very efficiently clear synaptically released GABA from the extracellular space, and thus exert a tight control on GABAergic inhibition. In neocortex, GABAergic inhibition is heavily recruited during recurrent phases of spontaneous action potent...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-09-01
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Series: | Frontiers in Neural Circuits |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00141/full |