Impairment of GABA transporter GAT-1 terminates cortical recurrent network activity via enhanced phasic inhibition

In the central nervous system, GABA transporters (GATs) very efficiently clear synaptically released GABA from the extracellular space, and thus exert a tight control on GABAergic inhibition. In neocortex, GABAergic inhibition is heavily recruited during recurrent phases of spontaneous action potent...

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Bibliographic Details
Main Authors: Daniel Simon Razik, David Johannes Hawellek, Bernd eAntkowiak, Harald eHentschke
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00141/full