ZEB1 Is a Transcription Factor That Is Prognostic and Predictive in Diffuse Gliomas

ZEB1 Is a Transcription Factor That Is Prognostic and Predictive in Diffuse Gliomas

Objective: To address the unmet medical need to better prognosticate patients with diffuse gliomas and to predict responses to chemotherapy regimens.Methods: ZEB1 alterations were retrospectively identified from a cohort of 1,160 diffuse glioma patients. Epigenome-wide association scans (EWAS) were...

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Bibliographic Details
Main Authors: Lincoln A. Edwards, Sungjin Kim, Mecca Madany, Miriam Nuno, Tom Thomas, Aiguo Li, Dror Berel, Bong-Sup Lee, Minzhi Liu, Keith L. Black, Xuemo Fan, Wei Zhang, John S. Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Neurology
Subjects:
ZEB1
copy number
decision curve analysis
diffuse gliomas
glioma stem cells (GSCs)
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01199/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.01199/full

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