Microglial activation and neuroinflammation in Alzheimer's disease: a critical examination of recent history

The neurofibrillary degeneration that occurs in Alzheimer’s disease (AD) is thought to be the result of a chronic and damaging neuroinflammatory response mediated by neurotoxic substances produced by activated microglial cells. This neuroinflammation hypothesis of AD pathogenesis has led t...

Full description

Bibliographic Details
Main Author: Wolfgang J Streit
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00022/full