Microglial activation and neuroinflammation in Alzheimer's disease: a critical examination of recent history
The neurofibrillary degeneration that occurs in Alzheimer’s disease (AD) is thought to be the result of a chronic and damaging neuroinflammatory response mediated by neurotoxic substances produced by activated microglial cells. This neuroinflammation hypothesis of AD pathogenesis has led t...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2010-06-01
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Series: | Frontiers in Aging Neuroscience |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00022/full |