Functional Profiling of Chondrogenically Induced Multipotent Stromal Cell Aggregates Reveals Transcriptomic and Emergent Morphological Phenotypes Predictive of Differentiation Capacity

Abstract Multipotent stromal cells (MSCs) are an attractive cell source for bone and cartilage tissue repair strategies. However, the functional heterogeneity of MSCs derived from different donors and manufacturing conditions has limited clinical translation, emphasizing the need for improved method...

Full description

Bibliographic Details
Main Authors: Johnny Lam, Ian H. Bellayr, Ross A. Marklein, Steven R. Bauer, Raj K. Puri, Kyung E. Sung
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.18-0065