Use of Busulfan to Condition Mice for Bone Marrow Transplantation

Summary: Myeloablative gamma irradiation has traditionally been used to condition mice prior to bone marrow transplantation. However, irradiation induces high levels of inflammation that may alter patterns of reconstitution. In addition, gamma irradiators are being removed from many facilities for s...

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Bibliographic Details
Main Authors: Encarnacion Montecino-Rodriguez, Kenneth Dorshkind
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:STAR Protocols
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720301465