Seasonal change in main alkaloids of jaborandi (Pilocarpus microphyllus Stapf ex Wardleworth), an economically important species from the Brazilian flora.

Pilocarpus microphyllus Stapf ex Wardleworth (jaborandi, Rutaceae) is one of the most important Brazilian medicinal species owing to its content of pilocarpine (PIL), an alkaloid used for treating glaucoma and xerostomia. This species contains another alkaloid, epiisopiloturine (EPI), which has demo...

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Main Authors: David Fernandes Lima, Luiza Ianny de Lima, Jefferson Almeida Rocha, Ivanilza Moreira de Andrade, Liliana Gonçalves Grazina, Caterina Villa, Liliana Meira, Leiz Maria Costa Véras, Iábita Fabiana Sousa Azevedo, Adriele Giaretta Biase, Joana Costa, Maria Beatriz P P Oliveira, Isabel Mafra, José Roberto de Souza de Almeida Leite
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5289444?pdf=render