TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1

TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1

Summary: Polyubiquitination of proliferating cell nuclear antigen (PCNA) regulates the error-free template-switching mechanism for the bypass of DNA lesions during DNA replication. PCNA polyubiquitination is critical for the maintenance of genomic integrity; however, the underlying mechanism is poor...

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Main Authors: Hyun Je Kang, Hyun Park, Eun Jin Yoo, Jun Ho Lee, Soo Youn Choi, Whaseon Lee-Kwon, Kyoo-young Lee, Jin-Hoe Hur, Jeong Kon Seo, Jae Sun Ra, Eun-A. Lee, Kyungjae Myung, Hyug Moo Kwon
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219302469

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http://www.sciencedirect.com/science/article/pii/S2589004219302469

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