CRISPulator: a discrete simulation tool for pooled genetic screens

Abstract Background The rapid adoption of CRISPR technology has enabled biomedical researchers to conduct CRISPR-based genetic screens in a pooled format. The quality of results from such screens is heavily dependent on the selection of optimal screen design parameters, which also affects cost and s...

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Bibliographic Details
Main Authors: Tamas Nagy, Martin Kampmann
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1759-9