Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation.

Identification of novel cellular proteins as substrates to viral proteases would provide a new insight into the mechanism of cell-virus interplay. Eight nuclear proteins as potential targets for enterovirus 71 (EV71) 3C protease (3C(pro)) cleavages were identified by 2D electrophoresis and MALDI-TOF...

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Bibliographic Details
Main Authors: Kuo-Feng Weng, Mei-Ling Li, Chuan-Tien Hung, Shin-Ru Shih
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2742901?pdf=render