Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer

Genomic characterization of co-existing neoplasia and carcinoma lesions reveals distinct evolutionary paths of gallbladder cancer

The progression from biliary tract intraepithelial neoplasia (BilIN) to gallbladder carcinoma (GBC) remains unclear. Here the authors use genomics to analyze coexisting GBC lesions, low-grade and high-grade BilINs, revealing two distinct evolutionary paths for GBC development.

Bibliographic Details
Main Authors: Jianzhen Lin, Xinxin Peng, Kun Dong, Junyu Long, Xuejiao Guo, Hongyue Li, Yi Bai, Xu Yang, Dongxu Wang, Xin Lu, Yilei Mao, Xinting Sang, Xuwo Ji, Haitao Zhao, Han Liang
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25012-9

Internet

https://doi.org/10.1038/s41467-021-25012-9

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