Cytotoxicity of some 1-(2,4-dihydroxyphenyl)-3-(4-phenylpiperidin-1-yl) prop-2-en-1-one derivatives using MTT assay
Some N-substituted piperidine structures were synthesized and evaluated for cytotoxic activity against four different cell lines using the standard MTT assay method and Doxorubicin was used as the reference drug. The result of cytotoxic activity as a measurement of IC50 values revealed that three of...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Shiraz University of Medical Sciences
2015-03-01
|
Series: | Trends in Pharmaceutical Sciences |
Online Access: | http://tips.sums.ac.ir/article_42148_09f3ffba36db07b9ba239df029a3e2d6.pdf |