A Low Iron Diet Protects from Steatohepatitis in a Mouse Model

A Low Iron Diet Protects from Steatohepatitis in a Mouse Model

High tissue iron levels are a risk factor for multiple chronic diseases including type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD). To investigate causal relationships and underlying mechanisms, we used an established NAFLD model—mice fed a high fat diet with s...

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Bibliographic Details
Main Authors: Lipika Salaye, Ielizaveta Bychkova, Sandy Sink, Alexander J. Kovalic, Manish S. Bharadwaj, Felipe Lorenzo, Shalini Jain, Alexandria V. Harrison, Ashley T. Davis, Katherine Turnbull, Nuwan T. Meegalla, Soh-hyun Lee, Robert Cooksey, George L. Donati, Kylie Kavanagh, Herbert L. Bonkovsky, Donald A. McClain
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Nutrients
Subjects:
iron
NAFLD
RNA-seq
metabolic syndrome
Online Access:https://www.mdpi.com/2072-6643/11/9/2172

Internet

https://www.mdpi.com/2072-6643/11/9/2172

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