A Simple and Highly Effective Method for the Stable Transduction of Uncultured Porcine Hepatocytes Using Lentiviral Vector

Gene therapy is an attractive approach for the treatment of a wide spectrum of liver diseases. Lentiviral vectors allow the stable integration of transgenes into the genome of nondividing differentiated cells including hepatocytes and could provide long-lasting expression of a therapeutic gene. To d...

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Bibliographic Details
Main Authors: Tuan Huy Nguyen, Tatiana Khakhoulina, Andrew Simmons, Philippe Morel, Didier Trono
Format: Article
Language:English
Published: SAGE Publishing 2005-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000005783982828