Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques.

<h4>Background</h4>Despite repeated outbreaks, in particular the devastating 2014-2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD). Among the drug candidates is the broad-spectrum polymerase inhibitor favipiravir, which showed a good to...

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Bibliographic Details
Main Authors: Jérémie Guedj, Géraldine Piorkowski, Frédéric Jacquot, Vincent Madelain, Thi Huyen Tram Nguyen, Anne Rodallec, Stephan Gunther, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002535