Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy

Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy

Abstract Objective Cardiomyocytes derived from human-induced pluripotent stem cells are a powerful platform for high-throughput drug screening in vitro. However, current modalities for drug testing, such as electrophysiology and fluorescence imaging have inherent drawbacks. To circumvent these probl...

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Bibliographic Details
Main Authors: Kazushi Suzuki, Takahito Onishi, Chieko Nakada, Shunsuke Takei, Matthew J. Daniels, Masahiro Nakano, Tomoki Matsuda, Takeharu Nagai
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Research Notes
Subjects:
hiPSC
Cardiomyocytes
Drug screening
Bioluminescence
Ca2+
Microscope
Online Access:http://link.springer.com/article/10.1186/s13104-018-3421-7

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http://link.springer.com/article/10.1186/s13104-018-3421-7

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