Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection.

Heme, an iron-containing organic ring, is essential for virtually all living organisms by serving as a prosthetic group in proteins that function in diverse cellular activities ranging from diatomic gas transport and sensing, to mitochondrial respiration, to detoxification. Cellular heme levels in m...

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Bibliographic Details
Main Authors: Amy Bergmann, Katherine Floyd, Melanie Key, Carly Dameron, Kerrick C Rees, L Brock Thornton, Daniel C Whitehead, Iqbal Hamza, Zhicheng Dou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008499