Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs.

Long noncoding RNA (lncRNA) transcripts have emerging impacts in cancer studies, which suggests their potential as novel therapeutic agents. However, the molecular mechanism behind their treatment effects is still unclear. Here, we designed a computational model to Associate LncRNAs with Anti-Cancer...

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Bibliographic Details
Main Authors: Yongcui Wang, Shilong Chen, Luonan Chen, Yong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007540