A resonance Rayleigh scattering sensor for sensitive differentiation of telomere DNA length and monitoring special motifs (G-quadruplex and i-motif) based on the Ag nanoclusters and NAND logic gate responding to chemical input signals

A resonance Rayleigh scattering sensor for sensitive differentiation of telomere DNA length and monitoring special motifs (G-quadruplex and i-motif) based on the Ag nanoclusters and NAND logic gate responding to chemical input signals

Abstract Background Differentiation of telomere length is of vital importance because telomere length is closely related with several deadly diseases such as cancer. Additionally, G-quadruplex and i-motif formation in telomeric DNA have been shown to act as a negative regulator of telomere elongatio...

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Bibliographic Details
Main Authors: Shuai Wang, Fei Qu, Wenli Han, Jinmao You
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Nanobiotechnology
Subjects:
Ag nanoclusters
Telomere DNA length
G-quadruplex
i-motif
DNA logic gate
Online Access:http://link.springer.com/article/10.1186/s12951-018-0407-5

Internet

http://link.springer.com/article/10.1186/s12951-018-0407-5

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