The Diversity and Similarity of Transmembrane Trimerization of TNF Receptors

Receptors in the tumor necrosis factor receptor superfamily (TNFRSF) regulate proliferation of immune cells or induce programmed cell death, and many of them are candidates for antibody-based immunotherapy. Previous studies on several death receptors in the TNFRSF including Fas, p75NTR, and DR5 show...

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Bibliographic Details
Main Authors: Linlin Zhao, Qingshan Fu, Liqiang Pan, Alessandro Piai, James J. Chou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NMR
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.569684/full