Hemodynamic analysis for stenosis microfluidic model of thrombosis with refined computational fluid dynamics simulation

Abstract Disturbed blood flow has been increasingly recognized for its critical role in platelet aggregation and thrombosis. Microfluidics with hump shaped contractions have been developed to mimic microvascular stenosis and recapitulate the prothrombotic effect of flow disturbance. However the phys...

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Bibliographic Details
Main Authors: Yunduo Charles Zhao, Parham Vatankhah, Tiffany Goh, Rhys Michelis, Kiarash Kyanian, Yingqi Zhang, Zhiyong Li, Lining Arnold Ju
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86310-2