Effects of Hyperhomocysteinemia on the Platelet-Driven Contraction of Blood Clots

Hyperhomocysteinemia (HHcy) is associated with thrombosis, but the mechanistic links between them are not understood. We studied effects of homocysteine (Hcy) on clot contraction in vitro and in a rat model of HHcy. Incubation of blood with exogenous Hcy for 1 min enhanced clot contraction, while 15...

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Bibliographic Details
Main Authors: Rustem I. Litvinov, Alina D. Peshkova, Giang Le Minh, Nail N. Khaertdinov, Natalia G. Evtugina, Guzel F. Sitdikova, John W. Weisel
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/6/354