Guidance from key organisations on exploring, confirming and interpreting subgroup effects of medical treatments: a scoping review

ObjectivesWith the increasing interest in personalised medicine, the use of subgroup analyses is likely to increase. Subgroup analyses are challenging and often misused, possibly leading to false interpretations of the effect. It remains unclear to what extent key organisations warn for such pitfall...

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Bibliographic Details
Main Authors: Maroeska M Rovers, Stan R W Wijn, Ly H Le, Michail Belias, Jeroen Hoogland, Thomas Debray
Format: Article
Language:English
Published: BMJ Publishing Group 2019-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/8/e028751.full