CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10–ERK signaling

CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10–ERK signaling

Abstract The chromobox (CBX) proteins mediate epigenetic gene silencing and have been implicated in the cancer development. By analyzing eight CBX family members in TCGA dataset, we found that chromobox 7 (CBX7) was the most strikingly downregulated CBX family member in urinary bladder cancer (UBC),...

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Bibliographic Details
Main Authors: Zhengnan Huang, Yilin Yan, Zhen Zhu, Jiakuan Liu, Xiao He, Sumiya Dalangood, Meiqian Li, Mingyue Tan, Jinming Cai, Pengfei Tang, Ruimin Huang, Bing Shen, Jun Yan
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03819-0

Internet

https://doi.org/10.1038/s41419-021-03819-0

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