Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice
OBJECTIVE: To investigate the antifibrotic effects of crocetin in scleroderma fibroblasts and in sclerotic mice. METHODS: Skin fibroblasts that were isolated from three systemic scleroderma (SSc) patients and three healthy subjects were treated with crocetin (0.1, 1 or 10 μM). Cell proliferation w...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculdade de Medicina / USP
2013-10-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013001001350&lng=en&tlng=en |