Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats

Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats

There is a transient increase in intracranial pressure (ICP) 18–24 h after ischaemic stroke in rats, which is prevented by short-duration hypothermia using rapid cooling methods. Clinical trials of long-duration hypothermia have been limited by feasibility and associated complications, which may be...

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Bibliographic Details
Main Authors: Daniel Omileke, Debbie Pepperall, Steven W. Bothwell, Nikolce Mackovski, Sara Azarpeykan, Daniel J. Beard, Kirsten Coupland, Adjanie Patabendige, Neil J. Spratt
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Neurology
Subjects:
intracranial pressure
hypothermia
middle cerebral artery occlusion
clinical translation
animal model
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.684353/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.684353/full

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