Gene expression signature of atypical breast hyperplasia and regulation by SFRP1

Gene expression signature of atypical breast hyperplasia and regulation by SFRP1

Abstract Background Atypical breast hyperplasias (AH) have a 10-year risk of progression to invasive cancer estimated at 4–7%, with the overall risk of developing breast cancer increased by ~ 4-fold. AH lesions are estrogen receptor alpha positive (ERα+) and represent risk indicators and/or precurso...

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Bibliographic Details
Main Authors: Kelly J. Gregory, Amy L. Roberts, Erin M. Conlon, Jacob A. Mayfield, Mary J. Hagen, Giovanna M. Crisi, Brooke A. Bentley, Jeffrey J. Kane, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl Simin, Jacob P. S. Johnson, Ashraf Khan, Ben R. Schneider, Sallie S. Schneider, D. Joseph Jerry
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Breast Cancer Research
Subjects:
Atypical hyperplasia
Breast
Lobular
Ductal
Premalignancy
SFRP1
Online Access:http://link.springer.com/article/10.1186/s13058-019-1157-5

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