Protease-activated receptor-1 negatively regulates proliferation of neural stem/progenitor cells derived from the hippocampal dentate gyrus of the adult mouse

Thrombin-activated protease-activated receptor (PAR)-1 regulates the proliferation of neural cells following brain injury. To elucidate the involvement of PAR-1 in the neurogenesis that occurs in the adult hippocampus, we examined whether PAR-1 regulated the proliferation of neural stem/progenitor c...

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Bibliographic Details
Main Authors: Masayuki Tanaka, Masanori Yoneyama, Tatsuo Shiba, Taro Yamaguchi, Kiyokazu Ogita
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300573