A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II.
During the acquisition of memories, influx of Ca2+ into the postsynaptic spine through the pores of activated N-methyl-D-aspartate-type glutamate receptors triggers processes that change the strength of excitatory synapses. The pattern of Ca2+influx during the first few seconds of activity is interp...
Main Authors: | Shirley Pepke, Tamara Kinzer-Ursem, Stefan Mihalas, Mary B Kennedy |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2820514?pdf=render |
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