Prenatal detection of aneuploidy and imbalanced chromosomal arrangements by massively parallel sequencing.

Prenatal detection of aneuploidy and imbalanced chromosomal arrangements by massively parallel sequencing.

Fetal chromosomal abnormalities are the most common reasons for invasive prenatal testing. Currently, G-band karyotyping and several molecular genetic methods have been established for diagnosis of chromosomal abnormalities. Although these testing methods are highly reliable, the major limitation re...

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Bibliographic Details
Main Authors: Shan Dan, Fang Chen, Kwong Wai Choy, Fuman Jiang, Jingrong Lin, Zhaoling Xuan, Wei Wang, Shengpei Chen, Xuchao Li, Hui Jiang, Tak Yeung Leung, Tze Kin Lau, Yue Su, Weiyuan Zhang, Xiuqing Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3289612?pdf=render

Internet

http://europepmc.org/articles/PMC3289612?pdf=render

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