The glycocalyx: a novel diagnostic and therapeutic target in sepsis

Abstract The glycocalyx is a gel-like layer covering the luminal surface of vascular endothelial cells. It is comprised of membrane-attached proteoglycans, glycosaminoglycan chains, glycoproteins, and adherent plasma proteins. The glycocalyx maintains homeostasis of the vasculature, including contro...

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Bibliographic Details
Main Authors: Ryo Uchimido, Eric P. Schmidt, Nathan I. Shapiro
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-018-2292-6