IGF-1R and Leptin Expression Profile and the Effects of Metformin Treatment on Metabolic and Endocrine Parameters in PCOS Mice

IGF-1R and Leptin Expression Profile and the Effects of Metformin Treatment on Metabolic and Endocrine Parameters in PCOS Mice

We aim to assess the effects of metformin treatment on metabolic and endocrine parameters and genes expression related to the insulin-responsive pathway in polycystic ovary syndrome (PCOS). This study comprises twenty-eight obese mice divided into three metformin-treated groups for seven and twenty...

Full description

Bibliographic Details
Main Authors: Luis Eduardo Prado Correia, Bruna Cristine de Almeida, Manuel de Jesus Simões, Mauro Abi Haidar, Daniela Berguio Vidotti, Ivaldo Silva
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/9058307

Internet

http://dx.doi.org/10.1155/2017/9058307

Similar Items