Novel Methylselenoesters as Antiproliferative Agents

Novel Methylselenoesters as Antiproliferative Agents

Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffold...

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Bibliographic Details
Main Authors: Nuria Díaz-Argelich, Ignacio Encío, Daniel Plano, Aristi P. Fernandes, Juan Antonio Palop, Carmen Sanmartín
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molecules
Subjects:
methylselenoester
methylselenol release
cytotoxicity
cell cycle arrest
cell death
thioredoxin reductase
Online Access:https://www.mdpi.com/1420-3049/22/8/1288

Internet

https://www.mdpi.com/1420-3049/22/8/1288

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