Anti-Japanese-encephalitis-viral effects of kaempferol and daidzin and their RNA-binding characteristics.

BACKGROUND: New therapeutic tools and molecular targets are needed for treatment of Japanese encephalitis virus (JEV) infections. JEV requires an α-1 translational frameshift to synthesize the NS1' protein required for viral neuroinvasiveness. Several flavonoids have been shown to possess antiv...

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Bibliographic Details
Main Authors: Ting Zhang, Zhiqiang Wu, Jiang Du, Yongfeng Hu, Liguo Liu, Fan Yang, Qi Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3262791?pdf=render