HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis

Cell death: Blocking the self-destruct mechanism Researchers have identified a compound that inhibits necroptosis, a type of programmed cell death that occurs naturally but that can be harmful when overactivated. Necroptosis helps defend against disease, triggering virus-infected cells to self-destr...

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Bibliographic Details
Main Authors: Han-Hee Park, Se-Yeon Park, Shinmee Mah, Jung-Hee Park, Soon-Sun Hong, Sungwoo Hong, You-Sun Kim
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0152-8