Improving l-threonine production in Escherichia coli by elimination of transporters ProP and ProVWX
Abstract Background Betaine, an osmoprotective compatible solute, has been used to improve l-threonine production in engineered Escherichia coli l-threonine producer. Betaine supplementation upregulates the expression of zwf encoding glucose-6-phosphate dehydrogenase, leading to the increase of NADP...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-03-01
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| Series: | Microbial Cell Factories |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12934-021-01546-x |