Enzymatic Kinetic Resolution of 2-Piperidineethanol for the Enantioselective Targeted and Diversity Oriented Synthesis

Enzymatic Kinetic Resolution of 2-Piperidineethanol for the Enantioselective Targeted and Diversity Oriented Synthesis

2-Piperidineethanol (1) and its corresponding N-protected aldehyde (2) were used for the synthesis of several natural and synthetic compounds. The existence of a stereocenter at position 2 of the piperidine skeleton and the presence of an easily-functionalized group, such as the alcohol, set 1 as a...

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Bibliographic Details
Main Authors: Dario Perdicchia, Michael S. Christodoulou, Gaia Fumagalli, Francesco Calogero, Cristina Marucci, Daniele Passarella
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
2-piperidineethanol
piperidine alkaloids
enzymatic resolution
alkaloid synthesis
Online Access:http://www.mdpi.com/1422-0067/17/1/17

Internet

http://www.mdpi.com/1422-0067/17/1/17

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