Lanosterol Synthase Pathway Alleviates Lens Opacity in Age-Related Cortical Cataract

Purpose. Lanosterol synthase (LSS) abnormity contributes to lens opacity in rats, mice, dogs, and human congenital cataract development. This study examined whether LSS pathway has a role in different subtypes of age-related cataract (ARC). Methods. A total of 390 patients with ARC and 88 age-matche...

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Bibliographic Details
Main Authors: Xinyue Shen, Manhui Zhu, Lihua Kang, Yuanyuan Tu, Lele Li, Rutan Zhang, Bai Qin, Mei Yang, Huaijin Guan
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2018/4125893