Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion

Roughly one-third of the human population is chronically infected with the intracellular single-celled parasite Toxoplasma gondii, but little is known about how this organism persists inside people. Previous research suggested that a parasite proteolytic enzyme, termed cathepsin protease L, is impor...

Full description

Bibliographic Details
Main Authors: Christian McDonald, David Smith, Manlio Di Cristina, Geetha Kannan, Zhicheng Dou, Vern B. Carruthers
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00869-19