The Calcium-Sensing Receptor Is Necessary for the Rapid Development of Hypercalcemia in Human Lung Squamous Cell Carcinoma

The calcium-sensing receptor (CaR) is responsible for the regulation of extracellular calcium (Ca2+o) homeostasis. CaR activation has been shown to increase proliferation in several cancer cell lines; however, its presence or function has never been documented in lung cancer. We report that Ca2+o-a...

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Bibliographic Details
Main Authors: Gwendolen Lorch, Serge Viatchenko-Karpinski, Hsiang-Ting Ho, Wessel P. Dirksen, Ramiro E. Toribio, John Foley, Sandor Györke, Thomas J. Rosol
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800606