Personal Neoantigens From Patients With NSCLC Induce Efficient Antitumor Responses

Personal Neoantigens From Patients With NSCLC Induce Efficient Antitumor Responses

ObjectiveTo develop a neoantigen-targeted personalized cancer treatment for non-small cell lung cancer (NSCLC), neoantigens were obtained from collected human lung cancer samples, and the utility of neoantigen and neoantigen-reactive T cells (NRTs) was assessed.MethodsTumor specimens from three pati...

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Bibliographic Details
Main Authors: Wei Zhang, Qi Yin, Haidong Huang, Jingjing Lu, Hao Qin, Si Chen, Wenjun Zhang, Xiaoping Su, Weihong Sun, Yuchao Dong, Qiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
neoantigen
neoantigen-reactive T cells (NRTs)
non-small cell lung cancer (NSCLC)
tumor vaccine
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.628456/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.628456/full

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