Short-term repeated HRV-16 exposure results in an attenuated immune response in vivo in humans.

Naturally, development of adaptive immunity following HRV infection affects the immune response. However, it is currently unclear whether or not HRV re-exposure within a short time frame leads to an altered innate immune response. The "experimental cold model" is used to investigate the pa...

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Bibliographic Details
Main Authors: Rebecca M Koch, Matthijs Kox, Corné van den Kieboom, Gerben Ferwerda, Jelle Gerretsen, Sandra Ten Bruggencate, Johannes G van der Hoeven, Marien I de Jonge, Peter Pickkers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5813921?pdf=render