RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis

<p>Abstract</p> <p>Background</p> <p>Idiopathic Pulmonary Fibrosis (IPF) is a debilitating disease characterized by exaggerated extracellular matrix deposition and aggressive lung structural remodeling. Disease pathogenesis is driven by fibroblastic foci formation, cons...

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Bibliographic Details
Main Authors: Hoban PR, Cottrell E, Watts KL, Spiteri MA
Format: Article
Language:English
Published: BMC 2006-06-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/88