Concentration independent modulation of local micromechanics in a fibrin gel.

Concentration independent modulation of local micromechanics in a fibrin gel.

Methods for tuning extracellular matrix (ECM) mechanics in 3D cell culture that rely on increasing the concentration of either protein or cross-linking molecules fail to control important parameters such as pore size, ligand density, and molecular diffusivity. Alternatively, ECM stiffness can be mod...

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Bibliographic Details
Main Authors: Maxwell A Kotlarchyk, Samir G Shreim, Martha B Alvarez-Elizondo, Laura C Estrada, Rahul Singh, Lorenzo Valdevit, Ekaterina Kniazeva, Enrico Gratton, Andrew J Putnam, Elliot L Botvinick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3100350?pdf=render

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http://europepmc.org/articles/PMC3100350?pdf=render

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