Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration

Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration

The major pathway for the production of the low-abundance membrane lipid phosphatidylinositol 3-phosphate (PI(3)P) synthesis is catalyzed by class III phosphoinositide 3-kinase (PI3K) Vps34. The absence of Vps34 was previously found to disrupt autophagy and other membrane-trafficking pathways in som...

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Bibliographic Details
Main Authors: Ammaji Rajala, Feng He, Robert E. Anderson, Theodore G. Wensel, Raju V. S. Rajala
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biology
Subjects:
phosphatidylinositol 3-phosphate
class III PI3K
Vps34
phosphoinositides
retinal degeneration
phosphorylation
Online Access:https://www.mdpi.com/2079-7737/9/11/384

Internet

https://www.mdpi.com/2079-7737/9/11/384

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