An integrative approach for building personalized gene regulatory networks for precision medicine
Abstract Only a small fraction of patients respond to the drug prescribed to treat their disease, which means that most are at risk of unnecessary exposure to side effects through ineffective drugs. This inter-individual variation in drug response is driven by differences in gene interactions caused...
Main Authors: | Monique G. P. van der Wijst, Dylan H. de Vries, Harm Brugge, Harm-Jan Westra, Lude Franke |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-12-01
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Series: | Genome Medicine |
Online Access: | http://link.springer.com/article/10.1186/s13073-018-0608-4 |
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