An integrative approach for building personalized gene regulatory networks for precision medicine

Abstract Only a small fraction of patients respond to the drug prescribed to treat their disease, which means that most are at risk of unnecessary exposure to side effects through ineffective drugs. This inter-individual variation in drug response is driven by differences in gene interactions caused...

Full description

Bibliographic Details
Main Authors: Monique G. P. van der Wijst, Dylan H. de Vries, Harm Brugge, Harm-Jan Westra, Lude Franke
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-018-0608-4