The Diverse Consequences of <i>FOXC1</i> Deregulation in Cancer
Forkhead box C1 (FOXC1) is a transcription factor with essential roles in mesenchymal lineage specification and organ development during normal embryogenesis. In keeping with these developmental properties, mutations that impair the activity of FOXC1 result in the heritable Axenfeld-Rieger Syndrome...
Main Authors: | L. Niall Gilding, Tim C. P. Somervaille |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-02-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/2/184 |
Similar Items
-
Editorial: Characterizing the Multi-Faceted Dynamics of Tumor Cell Plasticity
by: Satyendra Chandra Tripathi, et al.
Published: (2021-01-01) -
Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors
by: Paola Maroni, et al.
Published: (2017-01-01) -
New Insights into the Role of Epithelial–Mesenchymal Transition during Aging
by: Francisco Santos, et al.
Published: (2019-02-01) -
Transcription Factor Reprogramming in the Inner Ear: Turning on Cell Fate Switches to Regenerate Sensory Hair Cells
by: Amrita A. Iyer, et al.
Published: (2021-03-01) -
The Post-Translational Regulation of Epithelial–Mesenchymal Transition-Inducing Transcription Factors in Cancer Metastasis
by: Eunjeong Kang, et al.
Published: (2021-03-01)