The Diverse Consequences of <i>FOXC1</i> Deregulation in Cancer

Forkhead box C1 (FOXC1) is a transcription factor with essential roles in mesenchymal lineage specification and organ development during normal embryogenesis. In keeping with these developmental properties, mutations that impair the activity of FOXC1 result in the heritable Axenfeld-Rieger Syndrome...

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Bibliographic Details
Main Authors: L. Niall Gilding, Tim C. P. Somervaille
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/2/184