Expansion of endothelial progenitor cells in high density dot culture of rat bone marrow cells.

In vitro expansion of endothelial progenitor cells (EPCs) remains a challenge in stem cell research and its application. We hypothesize that high density culture is able to expand EPCs from bone marrow by mimicking cell-cell interactions of the bone marrow niche. To test the hypothesis, rat bone mar...

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Bibliographic Details
Main Authors: Yang Lu, Yiyi Gong, Jie Lian, Ling Wang, James D Kretlow, Guangdong Zhou, Yilin Cao, Wei Liu, Wen Jie Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177845?pdf=render